To Our Shareholders and Stakeholders,

We hope this message finds you well in this season of fresh greenery.

We would like to express our sincere gratitude for your continued support and consideration.

FuturedMe Inc. will celebrate its 8th anniversary on June 26, 2026. We are deeply grateful for this milestone, which has been made possible entirely through the warm support and guidance of all of you.

This fiscal year, FuturedMe Inc. has entered a new phase of accelerating its research and development activities and business development, following our Series A investment and the continued selection of our project by NEDO.

In addition, with targeted protein degradation therapeutics having entered the market as approved drugs in the United States, the field of degrader drug discovery has moved into a new stage of social implementation.

FuturedMe has been working to establish a degrader drug discovery platform based on direct proteasomal degradation through CANDDY, our proprietary drug discovery technology originating in Japan and the first of its kind in the world.

This fiscal year will be an important year for completing our platform. We will devote our full efforts to building a foundation for growth that will connect the platform’s achievements to early revenue-generating businesses and, ultimately, to our pipeline.

“No patients without medicine” — by applying the science of CANDDY technology to targets that had previously been considered undruggable, we will continue striving to realize a future in which medicines are available to all patients.

We respectfully ask for your continued support and guidance.

Please accept this written greeting as our formal message on the occasion of FuturedMe’s 8th anniversary.

Sincerely yours,

June 2026
FuturedMe Inc.
Etsuko Miyamoto
Representative Director, CEO & CSO

P.S. Please note that our office will be closed on Friday, June 26, in observance of our company anniversary. We apologize for any inconvenience this may cause and appreciate your understanding.

In addition, beginning this fiscal year, we have decided to discontinue the dorayaki sweets that we have traditionally sent as anniversary gifts.

We sincerely regret any disappointment this may cause to those who looked forward to them each year. Going forward, we will strive to meet your expectations through the growth of our research and development activities and business.

We would be grateful for your kind understanding.